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Enterocyte Autoantibodies (GECAs) and HLA: Their Relationship with HIV Infection Pathogenesis.

Antonio Arnaiz-Villena1,2, Tomas Lledo1,2, Christian Vaquero-Yuste1,2

  • 1Department of Immunology, School of Medicine, University Complutense of Madrid, 28040 Madrid, Spain.

International Journal of Molecular Sciences
|February 13, 2026
PubMed
Summary

Gut epithelial cell autoantibodies (GECAs) and human leukocyte antigen (HLA) alleles are crucial factors in HIV/AIDS pathogenesis. Investigating these neglected markers may improve HIV management and understanding of immune dysfunction.

Keywords:
AIDSHIVHLA (human major histocompatibility complex)autoantiobodies against enterocytes (GECAs, gut epithelial cells autoantibodies)autoimmunitydiagnosisenterocytesimmune deficiencymicrogenobiomapathogenesisretrovirus

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