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Timing for Minimally Invasive Surgery in Lipoleiomyoma: Insights From Two Cases
Yoko Suzuki1,2, Sakura Kataoka1, Misato Ueda1
1Department of Obstetrics and Gynecology, Tokyo Metropolitan Police Hospital, Tokyo, Japan, keisatsubyoin.or.jp.
Case Reports in Obstetrics and Gynecology
|February 13, 2026
Summary
Lipoleiomyomas can grow large and mimic cancer, causing symptoms like postmenopausal bleeding. Minimally invasive surgery is a safe and effective treatment option when carefully planned.
Area of Science:
- Gynecologic Oncology
- Surgical Pathology
Background:
- Lipoleiomyomas, a rare subtype of leiomyoma, can exhibit significant hypertrophic growth.
- Tumor enlargement may lead to clinical presentations mimicking gynecologic malignancies, including postmenopausal bleeding.
Purpose of the Study:
- To present two cases of lipoleiomyoma illustrating typical clinical scenarios.
- To review the management strategies for lipoleiomyoma, focusing on surgical approaches.
- To evaluate the feasibility and safety of minimally invasive surgery (MIS) for lipoleiomyoma.
Main Methods:
- Case report of two patients with lipoleiomyoma.
- Literature review of 50 reported cases of lipoleiomyoma.
- Analysis of surgical management, including minimally invasive versus open procedures.
Main Results:
- Both presented cases highlighted classical clinical features and diagnostic challenges.
- A review of 50 cases found only 12 were managed with MIS, despite its accessibility.
- Minimally invasive laparoscopic approaches were found to be safe and feasible with proper planning.
Conclusions:
- Lipoleiomyoma requires careful evaluation due to its potential for misdiagnosis and malignant mimicry.
- Shared decision-making and patient education are crucial for appropriate management.
- MIS is a viable and recommended surgical option for lipoleiomyoma when indicated and meticulously planned.
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