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Updated: Feb 14, 2026

Synthesis of Platinum-nickel Nanowires and Optimization for Oxygen Reduction Performance
Published on: April 27, 2018
Reductive desymmetric silylation of biaryl bis(triflates) enabled by a chiral nickel/picolinamide complex
Zhe Chen1, Junjie Zhang1, Chuan Wang1
1Department of Chemistry, University of Science and Technology of China 96 Jinzhai Road Hefei Anhui 230026 P. R. China chuanw@ustc.edu.cn.
Abstract:
Given the importance of organosilicons and atropisomerism, there is a fundamental need to develop new methods to synthesize axially chiral biaryl silanes. By use of an easily accessible chiral picolinamide as a ligand and inexpensive nickel as a catalyst, we realize a desymmetric silylation of prochiral biaryl bis(triflates) with silyl chlorides under net reductive conditions. This cross-electrophile reaction offers a new approach to preparing highly enantioenriched C 1-symmetric axially chiral platform molecules, which incorporate both a silane and a triflate moiety as two distinct docking sites for various downstream derivatizations.
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