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Updated: Feb 14, 2026

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Early Detection of Drug-Induced Renal Hemodynamic Dysfunction Using Sonographic Technology in Rats
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One-Year Follow-Up of Red Yeast Rice-Associated Renal Dysfunction: A Report of Two Cases
Moe Ozawa1, Yuki Kawai1, Jin Oshikawa2
1Department of Nephrology and Hypertension, Saiseikai Yokohamashi Nanbu Hospital, Yokohama, JPN.
Cureus
|February 13, 2026
Summary
Red yeast rice supplements caused kidney damage and Fanconi syndrome. Discontinuation led to partial or full renal recovery in two patients, suggesting gradual improvement over time.
Area of Science:
- Nephrology
- Pharmacology
Background:
- Red yeast rice (RYR) supplements are used for hyperlipidemia.
- RYR supplements (Beni-koji tablets) were recalled in Japan due to renal dysfunction.
- RYR-induced renal dysfunction can cause Fanconi syndrome and reduced estimated glomerular filtration rate.
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