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Updated: Feb 14, 2026

Application of the Intelligent High-Throughput Antimicrobial Sensitivity Testing/Phage Screening System and Lar Index of Antimicrobial Resistance
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Application of the Intelligent High-Throughput Antimicrobial Sensitivity Testing/Phage Screening System and Lar Index of Antimicrobial Resistance

Published on: July 21, 2023

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Current status of antimicrobial resistance in Indian healthcare system: combating antimicrobial resistance with

Ashish Shinde1, Athira Mohan1, Vani Mahathi Bulusu1

  • 1Department of Translational Medicine, All India Institute of Medical Sciences, Bhopal, India.

Frontiers in Antibiotics
|February 13, 2026
PubMed

Insights

This review integrates antimicrobial resistance data from Indian outpatient settings, highlighting community-level impacts. It proposes a novel framework linking precision medicine and AMR mitigation for personalized therapies in India.

Area of Science:

  • Public Health
  • Genomics
  • Infectious Diseases

Background:

  • Antimicrobial resistance (AMR) is a growing global threat.
  • Existing research often overlooks outpatient settings and community-level AMR data in India.
  • There is a need for integrated approaches to combat AMR in resource-limited settings.

Purpose of the Study:

  • To provide a unique perspective on AMR in Indian healthcare, focusing on outpatient settings.
  • To explore the community dimension of AMR and its public health implications.
  • To introduce an innovative framework linking AMR mitigation with precision medicine.

Main Methods:

  • Review and integration of existing antimicrobial resistance (AMR) data from Indian healthcare.
  • Emphasis on community and outpatient settings.
  • Development of a framework connecting AMR mitigation strategies with precision medicine (pharmacogenomics, metabolomics, proteomics, transcriptomics).

Main Results:

  • Highlights the under-explored community dimension of AMR in India.
  • Presents a novel framework integrating multi-omics data with national surveillance and stewardship.
  • Demonstrates the translational potential of personalized antimicrobial therapy in the Indian context.

Conclusions:

  • An integrated approach combining multi-omics, surveillance, and stewardship is crucial for AMR control.
  • Personalized antimicrobial therapy holds significant promise for the Indian healthcare ecosystem.
  • This review offers a new direction for AMR research and policy, bridging genomics and clinical practice in resource-limited settings.
Keywords:
AMRAcinetobacter baumaniiCREMDR-GNBantimicrobial resistancecarbapenem-resistant Enterobacteralesmulti-drug-resistant gram-negative bacteria

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