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Updated: Feb 14, 2026

In Vivo Functional Study of Disease-associated Rare Human Variants Using Drosophila
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In Vivo Functional Study of Disease-associated Rare Human Variants Using Drosophila

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Soluble SORL1 in cerebrospinal fluid as a marker for functional impact of rare SORL1 variants

Matthijs W J de Waal1,2,3, Sven J van der Lee1,3,4, Melanie Lunding5

  • 1Genomics of Neurodegenerative Diseases and Aging, Human Genetics, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.

Alzheimer'S & Dementia : the Journal of the Alzheimer'S Association
|February 13, 2026
PubMed
Abstract

Keywords:
Alzheimer's DiseaseSORL1cerebrospinal fluid (CSF)missense variantsquantitative immunoassaysoluble SORL1 (sSORL1)

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