Geriatric nutritional risk index is associated with erectile dysfunction.

Area of Science:

• Geriatric Medicine
• Nutritional Science
• Urology

Background:

• The geriatric nutritional risk index (GNRI) is a key tool for assessing nutritional status in older adults.
• Erectile dysfunction (ED) is a common condition affecting older men, with potential links to overall health.

Purpose of the Study:

• To investigate the association between the geriatric nutritional risk index (GNRI) and the risk of developing erectile dysfunction (ED).
• To determine if GNRI can serve as a predictive marker for ED in the elderly population.

Main Methods:

• Utilized multiple linear and logistic regression models to analyze the relationship between GNRI and ED risk in 1898 participants.
• Employed smooth curve fitting to assess nonlinear associations and conducted subgroup analyses, interaction tests, and sensitivity analyses for robustness.
• Evaluated GNRI's predictive capability for ED occurrence using receiver operating characteristic (ROC) curve analysis.

Main Results:

• A significant negative association was observed between GNRI and ED risk; a 1-unit increase in GNRI correlated with a 4% decrease in ED risk (OR=0.96).
• Individuals in the high GNRI group (≥98) showed a 35% lower risk of ED compared to the low GNRI group (<98).
• ROC analysis indicated a good predictive ability for GNRI in forecasting ED, with an area under the curve of 0.651.

Conclusions:

• Higher GNRI scores are independently and reliably associated with a reduced risk of erectile dysfunction in older adults.
• GNRI demonstrates potential as a valuable, non-invasive tool for predicting ED risk in geriatric populations.