Related Experiment Video
Updated: Feb 15, 2026

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease
Published on: June 16, 2020
Analysis of risk factors for frailty in older inpatients with interstitial lung disease
Yan Chen1,2, Xuemei Zhu2, Jing Wei1,2
1Department of Nursing, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Objective:
To investigate the frailty status and associated risk factors in older patients diagnosed with interstitial lung disease (ILD).
Methods:
A total of 242 older ILD patients admitted to the hospital between April 2023 and April 2024 were recruited using a cluster sampling method. Comprehensive clinical data were collected, including information from the General Data Questionnaire, the Fried Frailty Phenotype (FFP) Scale, the Dyspnea Scale, the Hospital Anxiety and Depression Scale, the Pittsburgh Sleep Quality Index, and the Self-Efficacy for Managing Chronic Disease Scale. Based on the Fried criteria, participants were categorized into two groups: the frailty group (FFP ≥ 3) and the non-frailty group (FFP < 3).
Results:
The prevalence of frailty among older patients with ILD was found to be 38.02%. Multivariate analysis revealed that age (OR = 1.064), polypharmacy (OR = 2.479), poor sleep quality (OR = 5.687), and dyspnea (OR = 10.316) were independent risk factors for frailty (P < 0.05).
Conclusions:
Frailty in older patients with ILD is significantly associated with age, polypharmacy, poor sleep quality, and dyspnea. Healthcare professionals, particularly nursing staff, should closely monitor frailty indicators in this population and implement timely, targeted interventions to mitigate its development and progression.
More Related Videos
05:53Measuring Frailty in HIV-infected Individuals. Identification of Frail Patients is the First Step to Amelioration and Reversal of Frailty
Published on: July 24, 2013
10:11Fundus Photography as a Convenient Tool to Study Microvascular Responses to Cardiovascular Disease Risk Factors in Epidemiological Studies
Published on: October 22, 2014
Related Concept Videos
Factors Affecting the Risk of Infection
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
Drug Toxicity: Risk factors
Lung Capacity
Factors Influencing Drug Absorption: Disease States and Pharmacology
Substances such as alcohol and specific drugs, including antineoplastics, can also negatively impact drug absorption. For instance,...
Pathophysiology of Peptic Ulcer Disease: Injurious Factors
In the antrum region, G cells secrete the gastrin hormone that binds to gastrin-cholecystokinin-B (CCK2) receptors on parietal and enterochromaffin-like (ECL) cells in the fundic glands. Simultaneously, the vagus nerve releases acetylcholine, which binds...
Relative Risk