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Related Experiment Video

Updated: Feb 15, 2026

Optimizing Photoneuromodulation Techniques to Evaluate the Role of Green Light-Emitting Diodes in Pain Management
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Emerging technologies in acute pain management.

Vendhan Ramanujam1, Haley Warzecha1, Yash Shah1

  • 1Anesthesiology, Rhode Island Hospital, Providence, RI, USA.

Pain Management
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PubMed
Summary
This summary is machine-generated.

Emerging technologies offer new non-opioid options for acute pain management, including digital tools and advanced drug delivery. Further research is needed to confirm their effectiveness and safety for diverse patients.

Keywords:
Acute painknowledge discoverynon-narcotic analgesicspain managementpostoperative paintechnology

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Area of Science:

  • Pain Management
  • Medical Technology
  • Pharmacology

Background:

  • Acute pain affects millions globally, often leading to opioid use.
  • Current treatments face challenges like opioid dependency and patient variability.
  • Multimodal analgesia advances still leave room for improvement.

Purpose of the Study:

  • To review recent evidence on emerging technologies for acute pain management.
  • To cover innovations in diagnostics, therapeutics, and drug delivery systems.
  • To identify non-opioid, patient-centered alternatives.

Main Methods:

  • Narrative review of studies from 2015-2025.
  • Searched PubMed and Embase databases.
  • Included studies showing positive evidence of technology investigation.

Main Results:

  • Identified digital pain scales, biosensors, VR, hypnosis, and music therapy.
  • Highlighted pharmacological advances: sublingual sufentanil, liposomal bupivacaine, Nav 1.8 inhibitors, cebranopadol, and tramadol-celecoxib co-crystals.
  • Noted novel delivery systems: oral patient-controlled analgesics, transdermal fentanyl, and bioresorbable nerve stimulators.

Conclusions:

  • Technological advancements are expanding acute pain management options.
  • Emerging tools offer non-opioid, precision-based alternatives.
  • Large-scale studies are needed to validate efficacy, safety, and cost-effectiveness.