Related Experiment Video
Updated: Feb 15, 2026

Author Spotlight: A Pseudotype Virus System for Assessing Omicron Subvariants and Neutralizing Antibodies in SARS-CoV-2 Research
Published on: September 8, 2023
Long-Term Risk of Incident Type 2 Diabetes Following SARS-CoV-2 Infection: A Population-Based Study in British
Héctor Alexander Velásquez García1,2, Stanley Wong1,2, Dahn Jeong1,2,3
1University of British Columbia Centre for Disease Control (UBC CDC), Vancouver, British Columbia, Canada.
Aims:
To assess the long-term risk of incident type 2 diabetes mellitus (T2DM) following SARS-CoV-2 infection in a large population-based cohort.
Materials And Methods:
We conducted a retrospective cohort study of all British Columbia residents aged ≥ 18 years tested for SARS-CoV-2 by reverse transcription polymerase chain reaction (RT-PCR) between 1 January 2020 and 31 January 2024. Individuals with pre-existing diabetes or residing in long-term care were excluded. Incident T2DM, identified more than 30 days after testing, was ascertained using a validated administrative algorithm. Inverse probability-weighted cause-specific hazard models estimated adjusted hazard ratios (HRs) for incident diabetes, accounting for death as a competing risk. Subgroup analyses examined associations by sex, age, vaccination status, COVID-19 severity, and follow-up duration.
Results:
Among 2,044,421 individuals (296,390 SARS-CoV-2-positive; 1,748,031 negative), 47,704 (2.33%) incident T2DM cases were identified over a median follow-up of 874 days. Compared with the SARS-CoV-2-negative group, the risk of diabetes was higher among infected individuals (HR 1.18; 95% CI: 1.15-1.22; p < 0.0001), rising progressively with illness severity-from ambulatory to hospitalised and intensive-care cases. No evidence of association was found among the vaccinated subgroups. The excess risk persisted for up to 3 years before waning thereafter.
Conclusions:
SARS-CoV-2 infection was associated with an increased risk of incident T2DM that persisted for up to 3 years, particularly among unvaccinated and severely ill individuals. These findings highlight the importance of post-infection metabolic surveillance and the potential protective role of vaccination.
More Related Videos
Related Concept Videos
Diabetes Mellitus: Type 2 and Gestational
meta-Directing Deactivators: –NO2, –CN, –CHO, –⁠CO2R, –COR, –CO2H
Types of Reports II: Incident or Occurrence Report
Purposes:
In the healthcare industry, reports play a crucial role in documenting incidents within an agency. The primary objective of these reports is to ensure patient safety, uphold the...
Factors Affecting the Risk of Infection
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
2° Amines to N-Nitrosamines: Reaction with NaNO2
SN2 Reaction: Kinetics
In a chemical reaction, a relationship exists between the concentration of reactants and the rate at which the reaction proceeds. The study to measure this relationship is known as the kinetics of a chemical reaction. Kinetic studies are used to deduce the rate law of a chemical reaction, which provides information about the species involved during the transition state of the rate-determining step. Thus, kinetic studies help to derive the mechanism of a...

