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Updated: Feb 16, 2026

Studying Triple Negative Breast Cancer Using Orthotopic Breast Cancer Model
Published on: March 20, 2020
Predictive factors assessment in breast cancer treatment
Abstract:
Breast cancer is the most common type of solid tumors in women. Breast cancer treatment at each stage of the disease is based on results describing genetic changes present in the tumor cells. Since breast cancer is not a homogeneous disease, its treatment approaches differ with respect to individual subgroups of breast cancer defined at the basic level by the expression of hormone receptors, HER2 receptor and Ki-67 marker. More recently described genetic changes in breast cancer cells significantly expand the treatment options, but on the other hand mean new challenges and demands in the further investigation of tumor samples. The following is a brief overview of prognostic and predictive markers used in breast cancer. The evaluation of these markers is in the hands of pathologists.
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