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Cannabis Use Among Individuals Treated with Medication for Opioid Use Disorder: Correlates, Patterns, and Motivations
Sarah E Leyde1, Joseph O Merrill1, Anna J Treadway2
1Department of Medicine, University of Washington School of Medicine, Seattle, WA, USA.
Frequent cannabis use is common in patients on medication for opioid use disorder (MOUD). This use is linked to anxiety, nausea, and lower employment, but not MOUD outcomes.
Area of Science:
- Addiction Medicine
- Psychiatry
- Psychology
Background:
- Cannabis use is prevalent among patients receiving medication for opioid use disorder (MOUD).
- Factors associated with frequent cannabis use in this population are not well understood.
- Understanding these factors is crucial for integrated care.
Purpose of the Study:
- To describe correlates, patterns, and motivations for cannabis use among individuals treated with MOUD.
- To identify factors associated with frequent cannabis use (≥3 days/week).
- To explore reasons for cannabis use, including symptom management and recreational purposes.
Main Methods:
- A randomized trial (n=303) compared frequent cannabis users with less frequent/non-users.
- Demographic and clinical characteristics were assessed.
- A subsample of frequent users completed a survey on usage patterns, motivations, and symptom management.
Main Results:
- 27% of participants used cannabis frequently (≥3 days/week).
- Frequent cannabis use was associated with anxiety, nausea, and lower employment.
- Individuals used cannabis for symptom management (stress, anxiety, pain, PTSD) and recreation; 52% desired to reduce use.
Conclusions:
- Frequent cannabis use in MOUD patients is linked to anxiety, nausea, and lower employment.
- No significant differences were observed in MOUD outcomes (substance use, retention).
- Increased attention to screening and treatment for co-occurring conditions like anxiety and pain is warranted.
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