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Updated: Feb 16, 2026

Walk with Me Hybrid Virtual/In-Person Walking for Older Adults with Neurodegenerative Disease
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Walking back to the snow.

Daniele Emedoli1, Luigi Albano2, Filippo Agnesi3

  • 1Modular Implantable Neuroprostheses (MINE) Laboratory, Università Vita-Salute San Raffaele & Scuola Superiore Sant'Anna, Milan, Italy; Department of Rehabilitation and Functional Recovery, IRCCS Ospedale San Raffaele, Milan, Italy.

Med (New York, N.Y.)
|February 14, 2026
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Summary
This summary is machine-generated.

A severe spinal cord injury patient regained walking ability through a personalized approach. This involved epidural electrical stimulation, custom orthoses, and tailored neurorehabilitation, enabling significant mobility milestones.

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Area of Science:

  • Neuroscience
  • Rehabilitation Medicine
  • Biomedical Engineering

Background:

  • Severe spinal cord injury presents significant challenges to motor function.
  • Restoring ambulation after spinal cord injury remains a major goal in neurorehabilitation.

Purpose of the Study:

  • To describe a patient-centered approach to restoring walking ability in an individual with severe spinal cord injury.
  • To highlight the combined use of advanced technologies and personalized therapy.

Main Methods:

  • Epidural electrical stimulation was applied to the lumbar spinal cord.
  • Custom-designed orthoses were utilized to support leg movements.
  • A personalized rehabilitation program was implemented, focusing on task-specific training.

Main Results:

  • The patient achieved the ability to walk again, demonstrating significant functional recovery.
  • Milestones included walking outdoors on challenging terrain, such as snow.
  • The combination of interventions led to substantial improvements in motor function and mobility.

Conclusions:

  • A multidisciplinary, patient-centered approach integrating epidural electrical stimulation, custom orthoses, and personalized rehabilitation can restore walking in severe spinal cord injury.
  • Tailored neurorehabilitation strategies are crucial for achieving functional gains and improving quality of life.