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DNBS/TNBS Colitis Models: Providing Insights Into Inflammatory Bowel Disease and Effects of Dietary Fat
Published on: February 27, 2014
Comparative effectiveness research in inflammatory bowel disease: Real-world evidence for real world decisions
Eathar Shakweh1, Ailsa Hart1, Nick Powell2
1Department of Metabolism, Digestion and Reproduction, Imperial College London, London, UK; Department of Gastroenterology, St Mark's Hospital and Academic Institute, London North West University Healthcare NHS Trust, London, UK.
None:
Placebo-controlled randomized controlled trials (RCTs) have long represented the sine qua non for determining treatment efficacy in inflammatory bowel disease (IBD). As the therapeutic armamentarium evolves and concerns regarding clinical equipoise intensify, there is increasing interest in comparative effectiveness research (CER). By harnessing real-world data, CER offers a powerful framework to inform treatment selection in an increasingly complex therapeutic environment.
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