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Can an antibiotic trigger a heart attack? Kounis syndrome induced by intraoperative amoxicillin allergy: a case
M Bernaola1, A Gago2, A Umpiérrez1
1Allergy Department, Hospital Central de la Defensa "Gómez Ulla", Madrid, Spain.
Abstract:
Kounis syndrome (KS) is an acute coronary syndrome triggered by mast cell degranulation in response to allergic or hypersensitivity reactions. Drug-induced KS, particularly due to antibiotics like amoxicillin, represents a severe and potentially life-threatening condition. This review aims to analyze the pathophysiology, clinical manifestations, diagnostic approaches, and management strategies of KS induced by amoxicillin allergy, with a focus on recent literature and emerging therapeutic insights.
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