Related Experiment Video

Updated: Feb 16, 2026

The Impact of Motor Task Conditions on Goal-Directed Arm Reaching Kinematics and Trunk Compensation in Chronic Stroke Survivors
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The Impact of Motor Task Conditions on Goal-Directed Arm Reaching Kinematics and Trunk Compensation in Chronic Stroke Survivors

Published on: May 2, 2021

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Factors Associated With Health-Related Quality of Life of Stroke Survivors: An Integrative Review

Anas Okour1, Tamilyn Bakas2, Elaine L Miller2

  • 1Montefiore School of Nursing, Mount Vernon, NY, USA aokour@montefiore.org okourao@mail.uc.edu.

Research and Theory for Nursing Practice
|February 14, 2026
PubMed

Insights

Stroke survivors often experience reduced quality of life in the first year. Key factors include symptom severity, functional disability, and individual characteristics, with support systems offering a buffer.

Area of Science:

  • Neurology
  • Public Health
  • Rehabilitation Medicine

Background:

  • Stroke significantly impairs neurological and functional abilities.
  • Health-related quality of life (HRQOL) is notably reduced in the first year post-stroke.

Purpose of the Study:

  • To identify critical factors influencing HRQOL in stroke survivors within the first year.
  • To explore the interplay between symptoms, functional status, and HRQOL.

Main Methods:

  • Integrative review of literature from January 2013 to December 2024.
  • Searches conducted in PubMed, CINAHL, and PsycINFO, adhering to PRISMA guidelines.
  • Methodological quality assessed using Johns Hopkins Nursing Evidence-Based Practice criteria.

Main Results:

  • Twenty-two studies (predominantly observational) were included.
  • Symptom severity (depression, anxiety, fatigue, stroke severity), functional disability (mobility), and individual factors (age, sex, education, resilience) negatively impacted HRQOL.
  • Environmental factors (social support, rehabilitation access) acted as protective buffers.

Conclusions:

  • Stroke survivors face significant risks to their quality of life in the first year.
  • HRQOL is primarily influenced by symptom burden and functional limitations, moderated by individual and environmental contexts.
  • Findings support interventions targeting symptom management, functional recovery, and personalized support.

Keywords:
functional disabilityhealth-related quality of lifeindividual characteristicsquality of lifestroke survivorssymptoms

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