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Related Concept Videos

Role of Skin in Vitamin D Synthesis01:23

Role of Skin in Vitamin D Synthesis

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The skin plays a crucial role in the synthesis of vitamin D, a vital nutrient for various physiological processes in the body. Vitamin D is unique because it can be synthesized in the skin through a series of chemical reactions triggered by exposure to ultraviolet B (UVB) radiation from sunlight.
The solar UV B rays (290-315 nm) are absorbed by the skin, and 7-dehydrocholesterol (provitamin D3) photolyzes it to previtamin D3, which undergoes a rapid transformation to vitamin...
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Connective Tissue Cell Types

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Connective tissue develops from the mesoderm of a developing embryo and consists of cells, fibers, and ground substance: a gel-like material containing large complexes of carbohydrates and proteins. Connective tissue was first identified as a separate tissue family in the 18th century, and Johannes Peter Muller coined the term connective tissue.
Fat cells (adipocytes), smooth muscle cells (myoblasts), and bone cells (osteoblasts) are some connective tissue cell types. Some immune system cells...
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Changes in Skin Color: Clinical Perspectives01:14

Changes in Skin Color: Clinical Perspectives

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The first thing a clinician sees is the skin, so the examination of the skin should be part of any thorough physical examination. Most skin disorders are relatively benign, but a few, including melanomas, can be fatal if untreated. A couple of the more noticeable disorders, albinism and vitiligo, affect the appearance of the skin and its accessory organs.
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Pigmentation01:19

Pigmentation

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The color of the skin is influenced by a number of pigments, including melanin, carotene, and hemoglobin. Recall that melanin is produced by cells called melanocytes, which are found scattered throughout the stratum basale of the epidermis. The melanin is transferred to the keratinocytes via melanosomes.
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The growth and maintenance of bone are regulated by a combination of nutritional factors, including vitamins, such as vitamin A, B12, C, D, and K.
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Vitamins

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Vitamins, derived from the Latin word for life, are essential organic substances required in small quantities for optimal growth and overall well-being. Unlike other organic nutrients, vitamins don't act as sources of energy or building materials but rather facilitate these nutrients' utilization by the body. Vitamins are predominantly coenzymes, assisting enzymes in specific chemical actions, like the oxidation of glucose for energy involving B vitamins. Most vitamins are not produced...
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Vitamin D in dermatology.

Dana Maria Khoury1, Abdul-Ghani Kibbi1

  • 1Department of Dermatology, American University of Beirut Medical Center, Beirut, Lebanon.

Clinics in Dermatology
|February 15, 2026
PubMed
Summary

Vitamin D plays a vital role in overall health, impacting skeletal and skin health. Maintaining optimal vitamin D levels is crucial due to its wide-ranging benefits.

Area of Science:

  • Endocrinology
  • Dermatology
  • Immunology

Background:

  • Vitamin D, the "sunshine vitamin", is synthesized in the skin via sun exposure or obtained through diet and supplements.
  • Its role extends beyond skeletal health, influencing cardiovascular, neurological, reproductive, infectious, autoimmune, and dermatological conditions.
  • As a pleiotropic hormone, vitamin D affects skin physiology, immune responses, and epidermal barrier function, impacting dermatoses.

Purpose of the Study:

  • To discuss the determinants of vitamin D status.
  • To highlight the advantages of maintaining adequate vitamin D levels.
  • To focus on the specific benefits of vitamin D for skin health.

Main Methods:

  • Literature review and synthesis of current research on vitamin D.

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  • Analysis of factors influencing vitamin D levels.
  • Examination of vitamin D's role in skin physiology and disease.

    • Main Results:

    • Vitamin D status is influenced by factors like skin type, sun exposure, BMI, and genetics.
    • Adequate vitamin D is linked to improved immune function and skin barrier integrity.
    • Vitamin D plays a significant role in the pathogenesis and severity of various skin conditions.

    Conclusions:

    • Optimal vitamin D status is increasingly recognized as essential for overall health.
    • Understanding vitamin D's multifaceted role is key to preventing and managing diseases, particularly dermatological ones.
    • Further research and public health initiatives should focus on ensuring adequate vitamin D levels in the population.