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Updated: Feb 17, 2026

Author Spotlight: Discovering New Biopesticides from Bioactive Soil Microbe-Derived Natural Products
Published on: July 26, 2024
Soil-associated microorganisms: A natural source of biologically active compounds
Nigora Rustamova1, Jakhongir Movlanov2, Dildora Alimova3
1Institute of Microbiology, Academy of Sciences of the Republic of Uzbekistan, Tashkent, Street Abdulla Kadiriy, Shaykhantakhur District, 7, B100128, Uzbekistan; Samarkand State University, University Boulevard 15, Samarkand, 703004, Uzbekistan.
None:
Soil-dwelling bacteria and fungi represent prolific sources of structurally diverse and biologically potent secondary metabolites. This review highlights 326 recently identified natural products isolated from various soil-associated microbial taxa, including both bacterial and fungal species. These metabolites, reported between 2018 and 2025, display a broad spectrum of bioactivities such as antimicrobial, anticancer, antifungal, antitumor, and enzyme-inhibitory effects. Emphasis is placed on the structural novelty and pharmacological relevance of these compounds, underscoring the continued importance of soil microbiota in the discovery of new therapeutic agents.
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