Long-term Oral Management for 2q37 Deletion Syndrome Patient.

Area of Science:

• Genetics
• Pediatric Dentistry
• Orthodontics

Background:

• 2q37 deletion syndrome is a rare chromosomal disorder with multisystem involvement.
• Dental findings in 2q37 deletion syndrome are poorly documented.
• This case highlights the oral characteristics and dental management of a pediatric patient.

Purpose of the Study:

• To describe the long-term dental management and oral characteristics of a pediatric patient with 2q37 deletion syndrome.
• To illustrate the challenges and successful outcomes in managing dental caries and malocclusion in this rare syndrome.

Main Methods:

• A case report of an 11-year-old boy with 2q37 deletion syndrome.
• Clinical examination revealed short stature, intellectual disability, tetralogy of Fallot, habitual vomiting, dental caries, and anterior crowding.
• Dental treatment included caries management and deferred orthodontic treatment due to cooperation issues, with follow-up over 7 years.

Main Results:

• The patient presented with significant dental caries, maxillary anterior crowding, high-arched palate, and mild dental erosion.
• After initial caries treatment, orthodontic treatment was initiated at age 18 years 2 months.
• Over a 10-year period, no new carious lesions developed, and significant improvement in anterior alignment was achieved with consistent caregiver engagement.

Conclusions:

• Long-term, consistent dental management is crucial for patients with 2q37 deletion syndrome.
• Successful orthodontic treatment can be achieved with improved patient cooperation and caregiver support.
• This case underscores the importance of addressing dental issues in rare genetic disorders.