Long-term Oral Management for 2q37 Deletion Syndrome Patient

2q37 deletion syndrome is an extremely rare chromosomal disorder, with approximately 150 cases reported worldwide. Affected individuals are known to have multisystem involvement, though dental findings associated with this syndrome remain poorly documented. This report describes the long-term dental management and oral characteristics of a pediatric patient with 2q37 deletion syndrome. The patient was an 11-year 2-monthold boy who presented with the chief complaints of dental caries and maxillary anterior crowding. Similarly to in previous reports regarding this syndrome, a clinical examination revealed short stature (120 cm, approximately 3 standard deviations below the mean), intellectual disability, tetralogy of Fallot, and habitual vomiting. Intraoral findings included 6 carious teeth, a high-arched palate, a constricted maxillary arch, and severe anterior crowding. Mild dental erosion associated with habitual vomiting was also noted. The initial dental treatment addressed the caries in the maxillary first molars and anterior teeth. Due to limited cooperation from the patient, orthodontic treatment was deferred, though regular follow-up examinations were conducted over a period of 7 years. Caregiver motivation remained high and patient cooperation improved, and sectional orthodontic treatment was initiated when he reached the age of 18 years 2 months. Throughout the approximately 10-year period of dental care, the mother of the patient, serving as caregiver, has remained consistently engaged, allowing for routine dental management to be maintained. No new carious lesions have developed during this period and notable improvement in anterior alignment has been achieved. Long-term follow-up will be continued.