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Updated: May 6, 2026

DiI-Labeling of DRG Neurons to Study Axonal Branching in a Whole Mount Preparation of Mouse Embryonic Spinal Cord
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Competitive and non-competitive rules govern activity-dependent axon arbor development in vivo.

Lucia Salatino1, Matías Rodriguez1, Paola V Plazas1,2

  • 1Instituto de Farmacología, Facultad de Medicina, Universidad de Buenos Aires, Buenos Aires C1121ABG, Argentina.

Development (Cambridge, England)
|February 16, 2026
PubMed
Summary

Spontaneous electrical activity (SEA) guides sensory circuit assembly. Suppressing SEA in zebrafish neurons revealed it controls axon growth and maturation through both competitive and non-competitive mechanisms.

Keywords:
Activity-dependentAxon arborDevelopmentLateral lineSensory systemsZebrafish

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