Hugo^TM RAS vs Da Vinci® Xi Robot-Assisted Partial Nephrectomy: First Propensity Score-Matched Comparison of...

Area of Science:

• Urology
• Surgical Technology
• Oncology

Background:

• Robot-assisted partial nephrectomy (RAPN) is a standard oncological procedure.
• The Da Vinci system has historically dominated robotic surgery.
• The Hugo™ RAS system represents a new competitor in the field.

Purpose of the Study:

• To conduct the first multicentric comparison between the Hugo™ RAS and Da Vinci® Xi systems for RAPN.
• To evaluate the safety and efficacy of the Hugo™ RAS system against a well-established platform.

Main Methods:

• A retrospective analysis of 258 patients undergoing off-clamp RAPN was performed.
• Propensity score matching (PSM) created two comparable cohorts (n=52 each) for Hugo™ RAS and Da Vinci® Xi.
• Key outcomes included surgical margins, complications (Clavien-Dindo grade ≥ 3), estimated glomerular filtration rate (eGFR) reduction, and Trifecta achievement.

Main Results:

• Both systems demonstrated comparable Trifecta rates (88.5% Hugo vs. 90.4% Da Vinci).
• No significant difference in positive surgical margins was observed (p=0.08).
• The Hugo cohort had a higher rate of postoperative transfusions (7.7% vs. 0%), but overall perioperative complications were similar (p=0.32).

Conclusions:

• The Hugo™ RAS system is a safe and viable alternative for RAPN.
• Perioperative surgical outcomes with the Hugo™ RAS system are comparable to the Da Vinci® Xi system.
• The introduction of the Hugo™ RAS system offers a competitive choice in robotic partial nephrectomy.