Related Experiment Video
Updated: Feb 17, 2026
07:57
An In Vitro Bladder Model of Catheter-Associated Urinary Tract Infection
Published on: June 24, 2025
1.3K
Urinary Tract Infections in Hospitalized Patients with Parkinson's Disease: Risk Factors and Outcomes
Hikaru Kamo1,2, Rachael M Burke1,3, Tejas R Mehta1
1Department of Neurology, Fixel Institute for Neurological Diseases, University of Florida, Gainesville, Florida, USA.
Movement Disorders Clinical Practice
|February 16, 2026
Summary
Urinary tract infections (UTIs) are common in hospitalized Parkinson's disease (PD) patients. Modifiable risk factors like emergent admission and catheter use increase UTI risk, leading to longer hospital stays.
Area of Science:
- Neurology
- Infectious Disease Epidemiology
- Health Services Research
Background:
- Urinary tract infections (UTIs) are frequent complications in hospitalized Parkinson's disease (PD) patients.
- UTIs contribute to adverse outcomes including delirium and extended hospital stays.
Purpose of the Study:
- To establish the prevalence of UTIs in hospitalized PD patients.
- To identify modifiable risk factors associated with UTIs.
- To evaluate the outcomes linked to UTIs in this population.
Main Methods:
- Retrospective cohort study utilizing the PINC-AI Healthcare Database.
- Inclusion of PD-related hospitalizations from 2019 to 2023.
- Identification of UTIs and multivariable analyses to determine associations.
Main Results:
- Over 321,000 PD hospitalizations were analyzed, with 18.9% having a UTI.
- Independent risk factors for UTI included emergent admission, inter-facility transfer, dementia, and indwelling urinary catheter use.
- Male sex was found to be a protective factor against UTI.
Conclusions:
- UTIs are prevalent in hospitalized PD patients and linked to significant adverse outcomes.
- Several modifiable risk factors for UTI were identified, offering targets for intervention.
- Findings support the development of PD-specific inpatient strategies for UTI prevention and risk assessment.
Related Concept Videos
01:25Urinary Tract Infection II: Pathophysiology
811
The pathophysiology of urinary tract infections (UTIs) encompasses several progressive stages, beginning with bacterial colonization and culminating in potential systemic complications if untreated. UTIs are primarily initiated by bacteria, such as Escherichia coli, which often originate from the gastrointestinal tract and migrate to the urinary system through the periurethral area. This migration can occur via several routes, including improper hygiene practices, sexual activity, or...
811
01:26Urinary Tract Infection I: Introduction
766
Urinary tract infections (UTIs) impact various parts of the urinary system, including the kidneys, ureters, bladder, and urethra. These infections are generally bacterial, with Escherichia coli being the most common causative agent, often originating from the gastrointestinal tract. However, other bacteria, such as Staphylococcus saprophyticus, Klebsiella pneumoniae, and Proteus mirabilis, are also known to cause UTIs. The type, location, and underlying complexity of the UTI guide both...
766
01:30Urinary Tract Infection III: Diagnostic Studies and Interprofessional Care
338
A healthcare provider can diagnose a urinary tract infection (UTI) through several methods:Medical History and Symptoms: The provider will take a detailed medical history and ask about symptoms such as frequent urination, burning sensation during urination, and lower abdominal pain.Urinalysis: A clean-catch urine sample is collected in a sterile container and tested for the presence of bacteria, white blood cells (leukocytes), nitrites, blood, and protein. The presence of leukocytes and...
338
01:17Urinary Tract Infection IV: Nursing Management
514
In managing urinary tract infections (UTIs) in nursing, a comprehensive assessment is essential. Begin by gathering subjective data, such as the patient’s complaints of dysuria (painful urination), urinary frequency, urgency, suprapubic pain, and any lower abdominal discomfort. This information can be complemented by questions regarding previous UTIs, sexual activity, and personal hygiene practices, which can provide insight into risk factors. Objective assessment should focus on signs...
514
01:15Parkinson's Disease: Overview
2.1K
Neurodegenerative disorders are progressive diseases that cause irreversible damage and loss to neurons in specific brain areas. Examples of these disorders include Parkinson's disease, Alzheimer's disease, Multiple Sclerosis (MS), and Amyotrophic Lateral Sclerosis (ALS). These disorders share characteristics such as proteinopathies, selective neuronal vulnerability, and a complex interplay between genetic and environmental factors. The primary therapeutic goal for these conditions is...
2.1K
01:24Parkinson's Disease: Treatment
1.2K
Neurodegenerative disorders, such as Parkinson's Disease (PD), involve the gradual and irreversible destruction of neurons in particular brain areas. These disorders exhibit standard features like proteinopathies, selective vulnerability of some neurons, and an interaction of intrinsic properties, genetics, and environmental influences in neural injury.
Parkinson's Disease is primarily a result of the loss of dopaminergic neurons in the substantia nigra pars compacta. The cornerstone of...
Parkinson's Disease is primarily a result of the loss of dopaminergic neurons in the substantia nigra pars compacta. The cornerstone of...
1.2K