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Published on: June 24, 2025
Urinary Tract Infections in Hospitalized Patients with Parkinson's Disease: Risk Factors and Outcomes
Hikaru Kamo1,2, Rachael M Burke1,3, Tejas R Mehta1
1Department of Neurology, Fixel Institute for Neurological Diseases, University of Florida, Gainesville, Florida, USA.
Background:
Urinary tract infections (UTIs) are common complications among hospitalized patients with Parkinson's disease (PD) and are associated with delirium and prolonged hospitalization.
Objectives:
To determine the prevalence of UTI, identify modifiable risk factors, and evaluate associated outcomes among hospitalized patients with PD.
Methods:
We conducted a retrospective cohort study using the PINC-AI Healthcare Database including PD-related hospitalizations from 2019 to 2023. UTIs diagnosed on admission or during hospitalization were identified, and multivariable analyses were performed.
Results:
Among more than 321,000 PD hospitalizations, 18.9% were associated with UTI. Emergent admission, inter-facility transfer, dementia, and indwelling urinary catheter use were independently associated with UTI, whereas male sex was protective. UTI was associated with prolonged length of stay and delirium.
Conclusions:
UTIs are frequent among hospitalized patients with PD and are associated with several modifiable risk factors. These findings may inform PD-specific inpatient strategies for UTI prevention and risk stratification.
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