Related Experiment Video
Updated: Feb 17, 2026

Global and Current Research Trends of Single-Cell Sequencing in Cancer: A Bibliometric and Visualization Study
Published on: April 18, 2025
Citespace-based visualization of nutritional research hotspots for oncology patients
Na Zhang1,2, Mei Li3, Jing Zhao1
1First Department of Thoracic Radiotherapy, The Fourth Hospital of Hebei Medical University, Shijiazhuang, Hebei, China.
Objective:
To analyze the current status of nutrition-related research on cancer patients in the past 20 years, explore the current research hotspots and frontiers, and provide references for nutrition-related research on cancer patients.
Methods:
Literature on cancer nutrition published between 1 January 2004 and 31 July 2024 was retrieved from the Web of Science Core Collection and the China National Knowledge Infrastructure (CNKI). CiteSpace 6.4. R1 was used for bibliometric analysis.
Results:
From Web of Science, 954 English-language articles were included, yielding nine clusters: gastrointestinal neoplasms-enteral nutrition, nutritional screening and assessment (covering nutrition assessment, nutrition screening, and nutrition risk index), sarcopenia, nutritional prehabilitation, risk, advanced cancer, and patient-generated subjective global assessment. From CNKI, 1,156 Chinese-language articles were included, forming eight clusters: enteral/parenteral nutrition, relative angle, nurse-led interventions, nutritional support, prognostic nutritional index, patients with gastrointestinal tumors, enhanced recovery after surgery, and nutritional risk assessment. Research centered on gastrointestinal cancer and perioperative care, with hotspots in malnutrition screening and assessment, sarcopenia, enhanced recovery, and prognosis.
Conclusion:
Cancer nutrition research is progressing steadily, with a predominant focus on evaluating and screening patients' nutritional status. Strengthening international and interdisciplinary collaboration and expanding the breadth and depth of inquiry will help advance this field.
Related Concept Videos
Cancer Survival Analysis
Mouse Models of Cancer Study
The development of transgenic, knockout, and knock-in mice has led to an exponential increase in their use as model organisms in research,...
Cancer-Critical Genes II: Tumor Suppressor Genes
When the function of certain critical genes, especially those involved in cell cycle regulation and cell growth signaling cascades, gets disrupted, it upsets the cell cycle progression. Such cells with unchecked cell cycles start proliferating uncontrollably and eventually develop into tumors.
Such genes that act...
Cancer-Critical Genes I: Proto-oncogenes
When the function of certain critical genes, especially those involved in cell cycle regulation and cell growth signaling cascades, gets disrupted, it upsets the cell cycle progression. Such cells with unchecked cell cycles start proliferating uncontrollably and eventually develop into tumors.
Such genes that act...
Cancer Therapies
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
mTOR Signaling and Cancer Progression
The mTOR pathway or the...

