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Re: Concomitant Bilateral Sacroiliitis and Lumbar Spondylodiscitis Secondary to Staphylococcus aureus Sepsis

Umut Bakay1

  • 1Department of Rheumatology, Denizli State Hospital, Denizli, Türkiye.

Journal of Clinical Practice and Research
|February 16, 2026
PubMed
Abstract

No abstract available in PubMed .

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Staphylococcus aureus is a Gram-positive coccus that resides harmlessly on the skin and mucous membranes of healthy individuals. When the skin barrier is breached, it can shift from a commensal to an opportunistic pathogen. This transition is facilitated by surface adhesins, such as clumping factor B and S. aureus surface protein G (SasG), which bind to structural proteins, including loricrin and cytokeratin, in the damaged epidermis. Protein A, another key factor, binds the Fc region of...