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Related Concept Videos

Appendicitis-II: Diagnostic Studies and Management01:29

Appendicitis-II: Diagnostic Studies and Management

604
Diagnosing and managing appendicitis requires a structured and comprehensive approach that spans from initial assessment to postoperative care. Here is an overview of the process:
Diagnosing Appendicitis
It requires a multifaceted approach, starting with a detailed physical examination to pinpoint the location and nature of the pain and identify any associated symptoms. Laboratory tests play a crucial role. A complete Blood Count (CBC) typically reveals leukocytosis (an increased number of...
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Appendicitis-I: Introduction01:22

Appendicitis-I: Introduction

2.7K
The appendix, a small, narrow, blind tube extending from the inferior part of the cecum, is widely regarded as a vestigial organ, having lost much of its original function through evolution. Despite its diminished role, the appendix can become inflamed, a condition known as appendicitis.
Etiology: Appendicitis can arise from various causes, primarily rooted in the obstruction of the appendix lumen. Factors contributing to this obstruction include fecal accumulation, lymphoid hyperplasia and, in...
2.7K

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Related Experiment Video

Updated: Feb 17, 2026

Murine Appendectomy Model of Chronic Colitis Associated Colorectal Cancer by Precise Localization of Caecal Patch
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Negative Appendectomy Rates and Their Correlation With the Use of Histopathology: A Clinical Audit.

Jamshid Khan1, Yasir Hakim2, Aalia Amjad2

  • 1General Surgery, Khyber Medical College, Peshawar, PAK.

Cureus
|February 16, 2026
PubMed
Summary

This study found a negative appendectomy rate below 5% by evaluating surgical residents' diagnostic skills against histopathology. Female and younger patients require closer attention to minimize this rate.

Keywords:
appendicitisclinical auditdiagnostic errorhistopathologynegative appendectomy

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Area of Science:

  • Medical Research
  • Surgical Audit
  • Clinical Diagnostics

Background:

  • Negative appendectomy rates are a key indicator of surgical diagnostic accuracy.
  • Assessing surgical residents' skills is crucial for improving patient outcomes.
  • Histopathology serves as the gold standard for diagnosing appendicitis.

Purpose of the Study:

  • To determine the negative appendectomy rate at a tertiary care hospital.
  • To evaluate the clinical diagnostic skills of surgical residents.
  • To identify patient demographics associated with higher negative appendectomy rates.

Main Methods:

  • A six-month clinical audit of 100 patients undergoing appendectomy.
  • Data collected via proformas, analyzed using SPSS version 23.0.
  • Comparison of clinical diagnosis with histopathology reports.

Main Results:

  • The overall negative appendectomy rate was less than 5%.
  • 89% of patients had acute appendicitis, 6% gangrenous, and 5% periappendicitis.
  • Younger patients (≤35 years) and females showed a potential trend towards increased negative appendectomies.

Conclusions:

  • The negative appendectomy rate in this cohort is acceptable.
  • Clinical diagnostic skills of surgical residents require ongoing assessment.
  • Targeted attention towards female and younger patients may further reduce negative appendectomy rates.