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Related Concept Videos

Assessment of Diffusion and Perfusion01:17

Assessment of Diffusion and Perfusion

Understanding and evaluating diffusion and perfusion is critical in assessing a patient's respiratory and circulatory health. These processes play key roles in maintaining the body's internal environment, ensuring that tissues receive adequate oxygen while waste products are efficiently removed.
The Role of Diffusion in Respiration
Diffusion is the process by which molecules move from an area of higher concentration to an area of lower concentration. In the respiratory system, this principle...

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Related Experiment Video

Updated: May 12, 2026

Management of Respiratory Motion Artefacts in 18F-fluorodeoxyglucose Positron Emission Tomography using an Amplitude-Based Optimal Respiratory Gating Algorithm
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A Device-Free Respiratory Gating Technique for Dynamic CT Using Time-Density Curve Analysis: A Technical Report With

Nobuyuki Akiyama1, Katsumi Tsujioka2, Tomoya Ushiroda1

  • 1Department of Radiology, Tosei General Hospital, Seto, JPN.

Cureus
|February 16, 2026
PubMed
Summary
This summary is machine-generated.

A new device-free respiratory gating technique uses chest wall CT data to track breathing. This method simplifies workflow and improves motion assessment for thoracic CT imaging.

Keywords:
ct coronary angiographydevice-free respiratory gatingdynamic computed tomographyfour-dimensional computed tomography (4d-ct)time-density curve

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Area of Science:

  • Medical Imaging
  • Radiology
  • Cardiovascular Imaging

Background:

  • Respiratory motion significantly challenges thoracic and cardiac CT image quality.
  • Conventional respiratory gating methods often require external devices, complicating workflow and limiting availability.

Purpose of the Study:

  • To develop a simple, device-free respiratory gating technique using intrinsic dynamic CT data.
  • To enable retrospective respiratory phase identification without external hardware.

Main Methods:

  • Analysis of time-density curves (TDC) from chest wall regions of interest (ROI) in dynamic CT data.
  • Generation of an intrinsic surrogate respiratory waveform from attenuation changes.
  • Application to lung tumor motion assessment and free-breathing coronary CT angiography (FB-CCTA).

Main Results:

  • Successfully generated a surrogate respiratory waveform directly from CT image data.
  • Demonstrated feasibility in clinical scenarios, including radiotherapy planning and FB-CCTA.
  • Eliminated complexity and synchronization issues associated with external monitoring devices.

Conclusions:

  • The proposed image-based approach offers a practical method for respiratory phase estimation in dynamic CT.
  • This technique can enhance the clinical utility of CT imaging, particularly when conventional breath-holding is impractical.