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Related Experiment Video

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Remotely Supervised Transcranial Direct Current Stimulation: An Update on Safety and Tolerability
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Optimized transcranial direct current stimulation for post-stroke dysphagia with small electrodes: a double-blind,

TaeYeong Kim1, Hae-Yeon Park2, Sung-Hwa Ko3

  • 1Research Institute, NEUROPHET Inc, Seoul, Republic of Korea.

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|February 16, 2026
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Summary

This study investigates personalized transcranial direct current stimulation (tDCS) for post-stroke dysphagia. Optimized, focal electrode placement improved swallowing function, showing feasibility for rehabilitation.

Keywords:
MRI-guided therapypersonalized neuromodulationpost-stroke dysphagia (PSD)small electrodetranscranial direct current stimulation

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Area of Science:

  • Neuroscience
  • Rehabilitation Medicine
  • Medical Engineering

Background:

  • Dysphagia (swallowing difficulty) affects a significant majority of post-stroke survivors.
  • Transcranial direct current stimulation (tDCS) shows promise for treating post-stroke dysphagia.
  • Individual brain anatomy influences tDCS effectiveness, necessitating personalized approaches.

Purpose of the Study:

  • To assess the safety and feasibility of using focalized, optimized tDCS electrode montages for post-stroke dysphagia.
  • To investigate the impact of individualized brain anatomy on tDCS treatment efficacy.
  • To improve swallowing function in post-stroke patients using tailored tDCS interventions.

Main Methods:

  • Recruitment of 30 participants, randomized into active or sham tDCS groups.
  • Utilizing computer modeling based on individual MRI to determine optimal tDCS electrode positions for maximal E-field strength in the swallowing motor cortex.
  • Application of tDCS (2 mA for 30 min, 20 sessions) using small, focal disk electrodes (R=1.5cm).

Main Results:

  • The study hypothesizes significant improvements in swallowing function in the active tDCS group compared to the sham group.
  • Primary outcomes include the Functional Oral Intake Scale (FOIS) and Penetration-aspiration Scale (PAS).
  • Secondary outcomes encompass the Videofluoroscopic Dysphagia Scale (VDS), voice quality, and cough strength.

Conclusions:

  • The study aims to establish the feasibility of personalized, focal-electrode tDCS interventions for post-stroke dysphagia rehabilitation.
  • Successful outcomes would support the use of tailored tDCS strategies to enhance swallowing function.
  • This research contributes to optimizing neurostimulation techniques for neurological recovery.