Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Magnetic Resonance Imaging01:24

Magnetic Resonance Imaging

9.9K
Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...
9.9K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Evaluation of the hyperspectral multicomponent calibration for plastic scintillation dosimetry.

Physics in medicine and biology·2026
Same author

Clinical validation of a high-definition mid-position magnetic resonance imaging approach for lung radiotherapy planning.

Medical physics·2026
Same author

Motion mitigation in positron-emission tomography guided radiotherapy delivered on a magnetic resonance imaging-linear accelerator.

Physics and imaging in radiation oncology·2026
Same author

MRI-guided radiotherapy: is the best still to come?

Physics in medicine and biology·2026
Same author

The first experimental implementation of real-time dose-guided MLC tracking using an MRI-linac.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology·2026
Same author

X-ray beam quality checks of a magnetic resonance-guided linear accelerator with its on-board megavoltage imager.

Physics and imaging in radiation oncology·2026

Related Experiment Video

Updated: Feb 17, 2026

Dynamic Lung Tumor Tracking for Stereotactic Ablative Body Radiation Therapy
08:17

Dynamic Lung Tumor Tracking for Stereotactic Ablative Body Radiation Therapy

Published on: June 7, 2015

16.3K

Real-time dose reconstruction and dose coverage forecasting using the magnetic resonance linear accelerator.

Peter R S Stijnman1, Pim T S Borman1, Stijn Oolbekkink1

  • 1Department of Radiotherapy, University Medical Center Utrecht, the Netherlands.

Physics and Imaging in Radiation Oncology
|February 16, 2026
PubMed
Summary
This summary is machine-generated.

Real-time dose monitoring during MR-Linac radiotherapy accurately tracks patient motion, enabling automatic treatment adjustments. This workflow forecasts accumulated dose, improving radiation therapy precision and patient outcomes.

Keywords:
Dose evaluationImage-guided radiotherapyReal-time

More Related Videos

Positron Emission Tomography-based Dose Painting Radiation Therapy in a Glioblastoma Rat Model using the Small Animal Radiation Research Platform
07:57

Positron Emission Tomography-based Dose Painting Radiation Therapy in a Glioblastoma Rat Model using the Small Animal Radiation Research Platform

Published on: March 24, 2022

3.2K
Proton Therapy Delivery and Its Clinical Application in Select Solid Tumor Malignancies
08:34

Proton Therapy Delivery and Its Clinical Application in Select Solid Tumor Malignancies

Published on: February 6, 2019

21.2K

Related Experiment Videos

Last Updated: Feb 17, 2026

Dynamic Lung Tumor Tracking for Stereotactic Ablative Body Radiation Therapy
08:17

Dynamic Lung Tumor Tracking for Stereotactic Ablative Body Radiation Therapy

Published on: June 7, 2015

16.3K
Positron Emission Tomography-based Dose Painting Radiation Therapy in a Glioblastoma Rat Model using the Small Animal Radiation Research Platform
07:57

Positron Emission Tomography-based Dose Painting Radiation Therapy in a Glioblastoma Rat Model using the Small Animal Radiation Research Platform

Published on: March 24, 2022

3.2K
Proton Therapy Delivery and Its Clinical Application in Select Solid Tumor Malignancies
08:34

Proton Therapy Delivery and Its Clinical Application in Select Solid Tumor Malignancies

Published on: February 6, 2019

21.2K

Area of Science:

  • Medical Physics
  • Radiation Oncology
  • Medical Imaging

Background:

  • Patient motion during radiotherapy causes dose deviations from the treatment plan.
  • Accurate dose monitoring is crucial for effective radiation therapy.

Purpose of the Study:

  • To develop and validate a workflow for real-time dose calculation and forecasting during MR-Linac treatments.
  • To enable real-time evaluation of dose guidance for adaptive radiotherapy.

Main Methods:

  • Collected data on treated anatomy, patient motion (rigid translations, 3D volumes), and linac status.
  • Performed real-time dose reconstruction and accumulated dose forecasting using MR imaging.
  • Validated calculations against diode and film measurements for rigid and deformable scenarios.

Main Results:

  • Real-time dose reconstruction showed a maximum standard deviation error of 2.3% compared to measured doses.
  • The workflow achieved real-time performance on a single GPU for 92% of the beam-on time.
  • Dose coverage forecasts were updated dynamically, becoming more frequent towards treatment end.

Conclusions:

  • Demonstrated feasibility of real-time dose distribution display and dose coverage forecasting with MR-Linac.
  • The workflow supports automatic plan adaptation and intrafraction drift corrections (IDCs).
  • This technology enhances precision in radiotherapy by accounting for intrafraction motion.