Related Experiment Video
Updated: Feb 17, 2026

The use of Biofeedback in Clinical Virtual Reality: The INTREPID Project
Published on: November 12, 2009
Extended reality interventions for health and procedural anxiety: An overview of reviews
Tom Arthur1, Sophie Robinson1, David Harris1
1Department of Public Health and Sports Sciences, Faculty of Health and Life Sciences, University of Exeter, Exeter, UK.
Background:
While Extended Reality (XR) technologies are becoming increasingly prevalent across society, there is a lack of consensus around their utilisation for the management of health and medical procedure anxieties. We undertook an overview of reviews to examine the effectiveness of these technology-based interventions.
Methods:
Data were extracted from full-text systematic reviews of patient-directed XR interventions for health and procedural anxiety. Records from the beginning of 2013 until 30 May 2023 were obtained from searches of MEDLINE, Embase, APA PsycINFO and Epistemonikos. Narrative synthesis then examined the consistency, quality and range of eligible research evidence, and reviews were appraised using the AMSTAR-2 tool.
Results:
We examined 56 reviews from diverse clinical contexts (35 of which included meta-analysis). Procedural anxieties were most commonly researched, including those relating to needle insertion, acute surgery, dental operations and/or wound care. Other studies focused on more general health anxieties, relating to longer-term treatment and rehabilitation, maternity and chronic conditions. A range of interventions (e.g. distraction- and exposure-based approaches) and technologies (e.g. immersive and non-immersive devices) have been evaluated, although comparisons between different types of interventions are lacking. While XR interventions were generally found to reduce patient anxiety, AMSTAR-2 evaluations highlighted 44/46 of the appraised reviews as low or critically low in quality, and intervention reporting was often lacking in detail.
Conclusions:
Evidence in support of XR interventions has not reached maturity and is currently lacking. Therefore, the emerging positive consensus for these techniques should be challenged, and the rationale for adopting such techniques in practice further considered.
Related Concept Videos
Behavior Therapy
Exposure therapy is a cornerstone of behavioral treatment for anxiety disorders. It involves systematic exposure to feared stimuli, either in real...
Anxiety: Overview
Individuals with anxiety often experience a range of physical and emotional symptoms, including sweating, trembling, tachycardia, and disturbances in sleep patterns. These symptoms vary in intensity and frequency but are generally disruptive and distressing.
Modeling in Therapy
Participant Modeling
Participant modeling involves therapists demonstrating calm and effective behaviors in...
Anxiolytic Drugs: Overview
Primary Types of Anxiolytic Drugs
1. Benzodiazepines:
Benzodiazepines bind to the GABA-A receptor in the brain, enhancing GABA's interaction. This action reduces neurotransmission, effectively blocking anxiety-associated limbic...
Operant Conditioning Intervention
In operant conditioning, behaviors that are...

