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Updated: Feb 17, 2026
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Published on: October 18, 2019
Hydrosilylation of Esters via a Titanocene(III) Borohydride-PMHS System: Scope, Limitations, and Mechanistic Insights
Godfred Fianu1, Jenna Azar1, Emmanuel Bulted1
1Department of Chemistry, Moravian University, Bethlehem, Pennsylvania 18018, United States.
Abstract:
The hydrosilylation of aromatic and aliphatic esters using catalytic amounts of titanocene-(III) borohydride and poly-(methylhydrosiloxane) (PMHS) as the terminal reductant is described. Alcohol yields range from 43% to 99%, with select esters requiring the addition of isopropanol to promote reactivity. This modification is proposed to facilitate in situ formation of a more reactive titanocene-(III) hydride species, which appears necessary for efficient ester reduction. This ester reduction protocol is mild, cost-effective, operationally simple and has potential utility in broader reductive transformations.
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