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A pathologically diagnosed multinodular and vacuolating neuronal tumor without typical multiple nodules: a case
Ryota Kitano1,2, Hiroaki Nagashima1, Tomoaki Harada1
1Department of Neurosurgery, Kobe University Graduate School of Medicine, Kobe, Japan.
Frontiers in Radiology
|February 16, 2026
Summary
Multinodular and vacuolating neuronal tumors (MVNT) are rare, grade 1 central nervous system tumors. This case report highlights key radiological features to differentiate MVNT from low-grade glioma, aiding accurate diagnosis.
Area of Science:
- Neuropathology
- Neuroncology
- Radiology
Background:
- Multinodular and vacuolating neuronal tumors (MVNT) are WHO grade 1 glioneuronal tumors.
- MVNTs are characterized by nodules in the deep cortex and subcortical white matter.
- Diagnosis is typically radiological, often not requiring treatment.
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