Related Experiment Video
Updated: May 2, 2026

Oral Biofilm Analysis of Palatal Expanders by Fluorescence In-Situ Hybridization and Confocal Laser Scanning Microscopy
Published on: October 20, 2011
Influence of Hyaluronic Acid Lip Filler Augmentation on Smile Design Parameters in Young Female Population: An
Ameer Biadsee1, Ameen Biadsee2, Haya Milhem1
1Department of Oral Rehabilitation, The Maurice and Gabriela Goldschleger School of Dental Medicine, Tel Aviv University, Tel Aviv, Israel, tau.ac.il.
Objective:
To evaluate the effect of hyaluronic acid (HA) lip augmentation on anterior tooth exposure and smile-line characteristics using three-dimensional (3D) facial scanning technology.
Materials And Methods:
Twenty-five female participants were enrolled. All injections were performed by a single experienced clinician following a standardized protocol, with a total of 1.0 mL of HA filler administered to the lips. 3D facial scans were obtained before treatment, immediately after injection, and at a 4-week follow-up. Maxillary left central incisor and canine exposure during smiling, as well as upper lip volume, were measured at each timepoint using dedicated software.
Results:
The mean participant age was 26.2 years, and the mean follow-up period was 28.8 days. At follow-up, maxillary central incisor and canine exposure decreased by 0.1 mm compared to pre-treatment values (p < 0.001). Upper lip volume increased by 0.79 mm3 at follow-up (p < 0.001). An inverse correlation was observed between lip volume and central incisor exposure, indicating reduced tooth display with increased lip volume. No significant correlation was found between lip volume and canine exposure or between central incisor and canine exposure.
Conclusion:
HA lip augmentation was associated with small but statistically significant changes in anterior tooth exposure during smiling. These findings highlight the influence of perioral soft tissue on smile-related dental parameters and underscore the importance of considering lip volume when planning esthetic dental and restorative treatments.
More Related Videos
19:53Single-stage Dynamic Reanimation of the Smile in Irreversible Facial Paralysis by Free Functional Muscle Transfer
Published on: March 1, 2015
07:16Author Spotlight: Development of a Novel Finite Element Analysis Model for Improved Orthognathic Surgical Techniques
Published on: October 20, 2023
Related Concept Videos
Assessment of the Mouth
Mouth Inspection
The inspection begins with visually examining the mouth for symmetry, color, and size.
Bioavailability Study Design: Healthy Subjects Versus Patients
Facial Feedback Hypothesis