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Treatment of Steroid-Refractory Immune Checkpoint-Related Hepatitis With Ruxolitinib

Vivian V Nguyen1, Malcolm Wells1, Carlos Moctezuma-Velazquez1

  • 1Division of Gastroenterology and Hepatology, University of Alberta, Edmonton, Alberta, Canada.

ACG Case Reports Journal
|February 16, 2026
PubMed
Summary

Immune-related hepatitis (IRH) is increasing with immune checkpoint inhibitors. Ruxolitinib showed promise as a rescue therapy for severe IRH when standard treatments failed.

Keywords:
immune checkpoint inhibitorsimmune-related hepatitisruxolitinibsteroid-refractory hepatitistocilizumab

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