Related Experiment Video
Updated: Feb 17, 2026

Analysis of Raw and Processed Cyperi Rhizoma Samples Using Liquid Chromatography-Tandem Mass Spectrometry in Rats with Primary Dysmenorrhea
Published on: December 23, 2022
Chrodrimanins U and V, meroterpenoids from an Alternaria sp
Peinan Fu1, Tingnan Zhou2, Feng Guo1
1School of Pharmacy, Jiangsu Food and Pharmaceutical Science College, Huaian, People's Republic of China.
Abstract:
Two new meroterpenoids, chrodrimanins U and V (1 and 2), and two known compounds 3-hydroxypentacecilide A (3) and chrodrimanin T (4) were obtained from the ascomycete fungus Alternaria sp. Structural characterisation was achieved through integrated spectroscopic techniques. The absolute configuration of each new meroterpenoid (1 and 2) was assigned via ECD calculations, respectively. None of the compounds (1-4) displayed cytotoxicity. In contrast, compounds 1 and 3 exhibited moderate inhibitory activity against H1N1, with IC50 values of 52.2 and 58.4 μM, respectively.
Related Concept Videos
Prochirality
Cholinergic Antagonists: Chemistry and Structure-Activity Relationship
Indirect-Acting Cholinergic Agonists: Chemistry and Structure-Activity Relationship
Reversible inhibitors display short to medium durations of action. Short-acting agents include simple alcohols with...
Direct-Acting Cholinergic Agonists: Chemistry and Structure-Activity Relationship
The direct-acting...
Antiasthma Drugs: Leukotriene Modifiers
Leukotriene modifiers work through two distinct mechanisms:
Plant Hormones

