Global & Community Health: Diagnosis and Management of Multiple Sclerosis in Nepal: Overcoming Barriers Through Local

Ayush Chandra1, Sudikshya Acharya2, Avinash Chandra3,4

  • 1Department of Medicine, Tianjin Medical University, China.

Neurology
|February 16, 2026
PubMed

Insights

Multiple sclerosis (MS) diagnosis and treatment face significant barriers in low-income countries. This study highlights challenges in Nepal and proposes practical, low-cost solutions for equitable care.

Area of Science:

  • Neurology
  • Immunology
  • Global Health

Background:

  • Multiple sclerosis (MS) is a prevalent CNS demyelinating disease affecting young adults.
  • MS is often underdiagnosed and undertreated in low and middle-income countries.
  • Challenges in Nepal include limited awareness, access to care, and high treatment costs.

Purpose of the Study:

  • To identify barriers to MS diagnosis and management in Nepal.
  • To propose context-specific adaptations for improving MS care.
  • To demonstrate strategies for equitable MS care in resource-constrained settings.

Main Methods:

  • Descriptive analysis of MS diagnosis and management challenges in Nepal.
  • Identification of barriers: awareness, access to neurology, MRI, lab testing, and treatment costs.
  • Outline of practical adaptations: simplified diagnostics, affordable therapies, and advocacy.

Main Results:

  • Key barriers identified: low public/clinician awareness, limited access to specialists and diagnostics (MRI, labs), and high long-term treatment costs.
  • Proposed adaptations include simplified diagnostic pathways and affordable immunosuppressive therapies.
  • The Multiple Sclerosis Society of Nepal plays a crucial role in advocacy for access and affordability.

Conclusions:

  • Addressing MS in resource-limited settings requires understanding local barriers.
  • Context-specific, low-cost strategies are essential for improving diagnosis and management.
  • Pragmatic approaches can enhance equitable access to MS care globally.

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