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Global & Community Health: Diagnosis and Management of Multiple Sclerosis in Nepal: Overcoming Barriers Through Local
Ayush Chandra1, Sudikshya Acharya2, Avinash Chandra3,4
1Department of Medicine, Tianjin Medical University, China.
Abstract:
Multiple sclerosis (MS) is the most common demyelinating disease of the CNS and disproportionately affects younger individuals, yet it remains underdiagnosed and undertreated in many low and middle-income countries. We describe key barriers to timely diagnosis and effective management of MS in Nepal, including limited public and clinician awareness; restricted access to neurologic care, MRI, and essential laboratory testing; and the high cost of long-term treatment. We also outline practical, context-specific adaptations such as simplified diagnostic pathways, use of affordable immunosuppressive therapies, and sustained advocacy by the Multiple Sclerosis Society of Nepal to improve access and affordability. Our experience illustrates pragmatic, low-cost strategies that may support more equitable MS care in resource-constrained settings.
Insights
Multiple sclerosis (MS) diagnosis and treatment face significant barriers in low-income countries. This study highlights challenges in Nepal and proposes practical, low-cost solutions for equitable care.
Area of Science:
- Neurology
- Immunology
- Global Health
Background:
- Multiple sclerosis (MS) is a prevalent CNS demyelinating disease affecting young adults.
- MS is often underdiagnosed and undertreated in low and middle-income countries.
- Challenges in Nepal include limited awareness, access to care, and high treatment costs.
Purpose of the Study:
- To identify barriers to MS diagnosis and management in Nepal.
- To propose context-specific adaptations for improving MS care.
- To demonstrate strategies for equitable MS care in resource-constrained settings.
Main Methods:
- Descriptive analysis of MS diagnosis and management challenges in Nepal.
- Identification of barriers: awareness, access to neurology, MRI, lab testing, and treatment costs.
- Outline of practical adaptations: simplified diagnostics, affordable therapies, and advocacy.
Main Results:
- Key barriers identified: low public/clinician awareness, limited access to specialists and diagnostics (MRI, labs), and high long-term treatment costs.
- Proposed adaptations include simplified diagnostic pathways and affordable immunosuppressive therapies.
- The Multiple Sclerosis Society of Nepal plays a crucial role in advocacy for access and affordability.
Conclusions:
- Addressing MS in resource-limited settings requires understanding local barriers.
- Context-specific, low-cost strategies are essential for improving diagnosis and management.
- Pragmatic approaches can enhance equitable access to MS care globally.
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