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Respiratory support during endotracheal intubation to improve intubation success in neonates

Poonam Singh1, Mayank Priyadarshi1, Suman Chaurasia1

  • 1Department of Neonatology, All India Institute of Medical Sciences, Rishikesh, India.

The Cochrane Database of Systematic Reviews
|February 17, 2026
PubMed

Insights

This review protocol assesses respiratory support during endotracheal intubation (ETI) for neonates. It aims to determine if respiratory support improves successful intubation rates compared to room air in NICU and delivery settings.

Area of Science:

  • Neonatal Medicine
  • Pediatric Critical Care
  • Respiratory Physiology

Background:

  • Endotracheal intubation (ETI) is a critical procedure in neonates.
  • Optimizing ETI success is vital for patient outcomes.
  • Current ETI practices often involve room air, but respiratory support is an alternative.

Purpose of the Study:

  • To evaluate the benefits and harms of respiratory support during ETI in neonates.
  • To compare the rate of successful intubation with respiratory support versus room air.
  • To inform best practices for neonatal intubation procedures.

Main Methods:

  • This is a protocol for a Cochrane Review.
  • The review will synthesize evidence from randomized controlled trials and observational studies.
  • Data on successful intubation, adverse events, and physiological parameters will be analyzed.

Main Results:

  • This section will be populated upon completion of the review.
  • Anticipated results will quantify the effectiveness of respiratory support in improving ETI success.
  • Potential harms associated with respiratory support will also be identified.

Conclusions:

  • This section will be populated upon completion of the review.
  • Conclusions will guide clinical decision-making regarding respiratory support during neonatal ETI.
  • The findings will contribute to evidence-based guidelines for neonatal airway management.
Abstract

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