CyberKnife radical cure for early lung adenocarcinoma: a case was confirmed by postoperative pathology

The utilization of pathological assessment to evaluate tumor response in patients with early-stage non-small cell lung cancer (NSCLC) has not been documented in the extant literature. A 64-year-old male patient with lung adenocarcinoma was treated with CyberKnife. A subsequent review of the images suggested that the mass in the area of radiotherapy had increased in size compared to the previous one, suggesting tumor recurrence. Consequently, surgery was performed to remove the enlarged mass. Postoperative histopathology showed no tumor tissue. This case underscores the potential efficacy of CyberKnife in the treatment of early-stage non-small cell lung cancer (NSCLC) tumors and confirms its effectiveness as a radical treatment modality, as validated by the gold standard of postoperative pathology.