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An open-source motion platform that replicates time synchronised internal and external patient motion for real-time
Alicja Kaczynska1, Chris Kuban2, Abbas Zahr2
1Image X Institute, Faculty of Medicine and Health, The University of Sydney, Sydney, Australia. alicja.kaczynska@sydney.edu.au.
Physical and Engineering Sciences in Medicine
|February 17, 2026
Summary
A new quality assurance device, the Internal-External Robotic Actuator (IntERAct), ensures accurate real-time image-guided radiotherapy. This novel platform validates tracking systems for internal tumor and external surface motion during radiation delivery.
Area of Science:
- Medical Physics
- Radiotherapy Technology
- Quality Assurance
Background:
- Real-time Image-guided Radiotherapy (IGRT) requires precise tracking of intra-fractional tumor motion.
- Robust quality assurance (QA) devices are essential for the clinical implementation of real-time IGRT.
Purpose of the Study:
- To develop and characterize a novel time-synchronized motion platform for QA of real-time IGRT systems.
- To create a device capable of monitoring combined internal and external patient motion.
Main Methods:
- Development of the Internal-External Robotic Actuator (IntERAct) QA device.
- Integration of a 6-degree-of-freedom (6DoF) robotic arm for internal motion and a 1-degree-of-freedom (1DoF) actuator for external motion.
- Validation using patient-measured lung and liver motion traces.
Main Results:
- The IntERAct device successfully replicated internal and external motion.
- Synchronization of internal and external motions achieved within 0.1 seconds.
- Geometric accuracy under two millimeters demonstrated.
Conclusions:
- The IntERAct device provides a robust and repeatable solution for QA of real-time IGRT.
- The open-source availability of the device facilitates its adoption by the medical physics community.
- This QA platform supports the safe and effective clinical use of advanced radiotherapy techniques.

