[Brain dissection in general pathology : Practical recommendations from a neuropathological perspective]

Since neuropathology departments in Germany are mainly located only at university hospitals, brain sections are frequently performed by general pathologists. This article provides practical recommendations for a structured approach and highlights situations in which neuropathological consultation is advisable.

The recommendations are based on established procedures, current literature, and personal professional experience. They are intended as a practical guide rather than a formal guideline.

Key steps for removal, fixation, and sectioning as well as interpretation of the findings are described. Hereby, the importance of clinical information and of a systematic assessment of macroscopic and histological changes is emphasized. Furthermore, typical situations are described in which neuropathological expertise is recommended.

A structured brain section enhances the overall quality of the autopsy. It enables a valid integration of cerebral changes into a broader context. Close collaboration between pathology and neuropathology is essential and beneficial for both sides.