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Updated: Feb 19, 2026

Therapy Testing in a Spheroid-based 3D Cell Culture Model for Head and Neck Squamous Cell Carcinoma
Published on: April 20, 2018
SEOM-TTCC clinical guideline for nasopharyngeal carcinoma (update 2025)
Antonio Rueda Domínguez1, Beatriz Cirauqui2, Almudena García Castaño3
1Medical Oncology Intercenter Unit, Regional and Virgen de La Victoria University Hospitals, IBIMA, 29010, Málaga, Spain. antonio.rueda.dominguez.sspa@juntadeandalucia.es.
Abstract:
Nasopharyngeal carcinoma is distinct from other cancers of the head and neck in biology, epidemiology, histology, natural history, and response to treatment. Radiotherapy is the cornerstone of locoregional treatment of non-disseminated disease and, in combination with chemotherapy, improves survival rates. In the case of metastatic disease stages, treatment requires platinum/gemcitabine-based chemotherapy, and patients may achieve a long survival time. In these guidelines (updated in 2025), we summarize current evidence and available therapies for the medical management of advanced nasopharyngeal carcinoma.
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