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Related Concept Videos

Chronic Kidney Disease III: Interprofessional Care01:28

Chronic Kidney Disease III: Interprofessional Care

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Chronic kidney disease (CKD) requires collaborative and comprehensive management. CKD progresses through stages and can lead to end-stage kidney disease (ESKD) if untreated. Interprofessional collaboration and patient education are crucial, enabling patients to manage their health and improve their quality of life.Diagnostic approach for chronic kidney diseaseThe diagnosis of CKD primarily focuses on the glomerular filtration rate (GFR), which assesses kidney function by measuring how well...
494
Chronic Kidney Disease IV: Nursing Management01:18

Chronic Kidney Disease IV: Nursing Management

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Nursing management is essential for preventing complications, maintaining stability, and improving patients' quality of life in chronic kidney disease (CKD). By using a structured approach, nurses help slow CKD progression and support effective patient care​.1. Comprehensive patient assessmentEffective management begins with nurses reviewing the patient’s medical history, and identifying key risk factors like diabetes, hypertension, and nephrotoxic drug use. Nurses assess signs of...
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Acute Kidney Injury V: Interprofessional Care01:20

Acute Kidney Injury V: Interprofessional Care

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Acute Kidney Injury (AKI) requires a collaborative healthcare approach to restore renal function and prevent complications. Essential management strategies involve monitoring fluid and electrolyte balance, adjusting medications, initiating dialysis when necessary, and providing nutritional support.Fluid and Electrolyte ManagementFluid Monitoring: Regularly monitoring body weight, central venous pressure, and urine output helps detect fluid imbalances early. Patient intake and output are...
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Chronic Kidney Disease I: Introduction01:25

Chronic Kidney Disease I: Introduction

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Chronic Kidney Disease (CKD) arises when the kidneys progressively lose their ability to function, ultimately leading to end-stage renal disease. At this advanced stage, the kidneys can no longer filter waste or maintain essential body functions, requiring renal replacement therapy (RRT) through dialysis or a kidney transplant for survival.Early-stage chronic kidney disease and detection challengesIn CKD's early stages, symptoms often remain absent because healthy nephrons compensate for...
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Chronic Kidney Disease II: Clinical Manifestations01:24

Chronic Kidney Disease II: Clinical Manifestations

730
Chronic Kidney Disease (CKD) progressively impairs multiple body systems due to the accumulation of uremic toxins, which disrupt cellular functions across various organs.Neurologic symptomsNeurologic symptoms often arise early in CKD, as uremic toxin buildup drives changes in cognitive and motor functions. Patients frequently experience fatigue, headache, confusion, difficulty concentrating, and, in severe cases, seizures. Peripheral neuropathy commonly manifests as burning sensations in the...
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Extracorporeal Removal of Drugs: Continuous Renal Replacement Therapy01:26

Extracorporeal Removal of Drugs: Continuous Renal Replacement Therapy

243
Continuous Renal Replacement Therapy (CRRT) is an essential intervention for patients experiencing severe kidney dysfunction. This therapy offers a continuous mechanism for removing fluids and toxins from the bloodstream, leveraging the patient’s blood pressure to facilitate filtration through a specialized filter. This method contrasts with intermittent dialysis, providing a gentler and more consistent removal of waste products and excess fluid, which is particularly beneficial in...
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5/6 Nephrectomy Using Sharp Bipolectomy Via Midline Laparotomy in Rats
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Workforce Detachment in Persons with CKD.

Rasmus Rørth1, Milos M Koch2, Thomas A Gerds1,2

  • 1Steno Diabetes Center Copenhagen, Copenhagen, Denmark.

Clinical Journal of the American Society of Nephrology : CJASN
|February 17, 2026
PubMed
Summary

Individuals with chronic kidney disease (CKD) face a significantly higher risk of leaving the workforce. Early detection and treatment interventions for CKD are crucial to mitigate this impact.

Keywords:
CKDchronic kidney failurediabetes mellitusepidemiologic methodsepidemiology and outcomes

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Area of Science:

  • Nephrology
  • Public Health
  • Occupational Medicine

Background:

  • Impaired kidney function is linked to adverse health outcomes, including mortality and reduced quality of life.
  • Employment status is closely tied to financial stability, health, and personal identity.
  • The relationship between kidney function and workforce participation requires further investigation.

Purpose of the Study:

  • To examine the association between chronic kidney disease (CKD) status and CKD stage with workforce detachment.
  • To estimate the absolute risk of workforce detachment in a working-age population with CKD.

Main Methods:

  • Utilized weekly updated occupational status data combined with laboratory results and national registries.
  • Estimated kidney function in a working-age population (18-60 years).
  • Employed the Aalen-Johansen estimator to account for competing risks of retirement and death.

Main Results:

  • Individuals with CKD exhibited a higher absolute risk of workforce detachment (1-year risk: 9% vs. 5%, p<0.001).
  • The risk of workforce detachment increased with CKD severity, ranging from 5% (eGFR>60) to 20% (CKD stage G5).
  • Factors such as older age, female sex, diabetes, and lower education levels were associated with increased workforce detachment.

Conclusions:

  • CKD significantly increases the likelihood of workforce detachment compared to normal kidney function.
  • This highlights an under-recognized burden of CKD.
  • Urgent need for early detection and treatment interventions for CKD is emphasized.