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Workforce Detachment in Persons with CKD
Rasmus Rørth1, Milos M Koch2, Thomas A Gerds1,2
1Steno Diabetes Center Copenhagen, Copenhagen, Denmark.
Clinical Journal of the American Society of Nephrology : CJASN
|February 17, 2026
Summary
Individuals with chronic kidney disease (CKD) face a significantly higher risk of leaving the workforce. Early detection and treatment interventions for CKD are crucial to mitigate this impact.
Area of Science:
- Nephrology
- Public Health
- Occupational Medicine
Background:
- Impaired kidney function is linked to adverse health outcomes, including mortality and reduced quality of life.
- Employment status is closely tied to financial stability, health, and personal identity.
- The relationship between kidney function and workforce participation requires further investigation.
Purpose of the Study:
- To examine the association between chronic kidney disease (CKD) status and CKD stage with workforce detachment.
- To estimate the absolute risk of workforce detachment in a working-age population with CKD.
Main Methods:
- Utilized weekly updated occupational status data combined with laboratory results and national registries.
- Estimated kidney function in a working-age population (18-60 years).
- Employed the Aalen-Johansen estimator to account for competing risks of retirement and death.
Main Results:
- Individuals with CKD exhibited a higher absolute risk of workforce detachment (1-year risk: 9% vs. 5%, p<0.001).
- The risk of workforce detachment increased with CKD severity, ranging from 5% (eGFR>60) to 20% (CKD stage G5).
- Factors such as older age, female sex, diabetes, and lower education levels were associated with increased workforce detachment.
Conclusions:
- CKD significantly increases the likelihood of workforce detachment compared to normal kidney function.
- This highlights an under-recognized burden of CKD.
- Urgent need for early detection and treatment interventions for CKD is emphasized.
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