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Updated: Feb 19, 2026

A "Dual-Addition" Calcium Fluorescence Assay for the High-Throughput Screening of Recombinant G Protein-Coupled Receptors
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The elephant in the adhesion GPCR room

Tobias Langenhan1,2,3

  • 1Rudolf Schönheimer Institute of Biochemistry, Division of General Biochemistry, Medical Faculty, Leipzig University, 04103 Leipzig, Germany.

Science Signaling
|February 17, 2026
PubMed
Summary

Adhesion G protein-coupled receptors (GPCRs) are crucial for organ system development. Bernadyn et al. reveal new details on the activation mechanism and cellular functions of the adhesion GPCR GPR97/ADGRG3.

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