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Published on: February 17, 2022
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Time of infusion does not significantly impact outcomes following CAR T-cell therapy in large B-cell lymphoma
Mark R Dowling1,2,3, Edward Robert Scheffer Cliff1,2, Anthony Jeffrey4,5
1Department of Clinical Haematology, Peter MacCallum Cancer Centre and The Royal Melbourne Hospital, Melbourne, Australia.
Blood
|February 17, 2026
Abstract:
In this retrospective analysis of 584 patients who received chimeric antigen receptor T-cell therapy for large B-cell lymphoma at 6 Australian centers, no association was found between time of infusion and outcome, accounting for confounders, suggesting minimal clinical impact of chronobiology in this setting.

