Virucidal multipurpose aqueous solution containing quaternary ammonium cation and sulfobetaine is effective against
Masahiko Morioka1, Yohei Takeda2, Mamoru Ohnishi3
1Future Cell Japan Corp., Tokyo Metropolitan Industrial Technology Research Institute 318, 2-4-10 Aomi Koto-ku, Tokyo 135-0064, Japan.
Abstract:
Highly pathogenic avian influenza virus (HPAIV) is an enveloped virus currently spreading among birds around the world, and infections in humans have been reported. Common disinfectants such as ethanol and chlorine are somewhat effective, but the development of more effective disinfectants to prevent infection is urgently needed. As a result of a series of studies focusing on cationic antibacterial agents, DEA-171 has been developed as a safe and effective anti-enveloped virus by adding sulfobetaine to a specific quaternary ammonium cation. This solution inactivated approximately 99.0% of H5 HPAIV in 30 min.
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