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An attempt to explore the relative importance of factors influencing medication adherence after percutaneous coronary

Haiyan Xu¹, Min Jiang², Qiangting Deng³

¹Experimental Research Center for Medical and Psychological Science, School of Psychology, Army Medical University, Chongqing, China.

European Journal of Cardiovascular Nursing

|February 17, 2026

Abstract

Aims:

To generally explore the relative importance of factors influencing medication adherence after percutaneous coronary intervention (PCI), and to provide a new perspective on the theoretical framework of medication adherence intervention.

Methods And Results:

A single-centre, cross-sectional study was conducted. Primary outcomes were indicators of medication nonadherence, including incorrect implementation behaviour, medication taking proportion <90% and discontinuation. Potential influencing factors included baseline characteristics at PCI and barriers to medication adherence after PCI. Binary logistic regression was used to analyse factors associated with the indicators. A total of 901 cases with valid data were identified. Incorrect implementation behaviour, medication taking proportion <90%, and discontinuation after PCI were 39.3%, 16.6%, and 8.9%, respectively. Rural residence, lacking medication necessary, and medication side effects were common factors associated with the above three indicators, and complex prescriptions, disturbing routine, age (at this PCI), number of coronary stents (up to this PCI), economic difficulties, memory decline, inconvenience, busy, and extensive travel were uncommon factors associated with these three indicators.

Conclusion:

Exploring the relative importance of factors influencing medication adherence after PCI provides a new perspective for integrating multifaceted and tailored interventions as a new system.

Keywords:

Influencing factors Medication adherence Medication adherence intervention Percutaneous coronary intervention (PCI)

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