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Updated: Feb 19, 2026

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The magnitude of multimorbidity in childhood: a global systematic review

Somen Kumar Pradhan1, Jogesh Murmu2, Upasana Nayak2

  • 1Maharaja Krushna Chandra Gajapati Medical College and Hospital Brahmapur, Ganjam, India.

Systematic Reviews
|February 18, 2026
PubMed

Insights

Childhood multimorbidity, the co-occurrence of multiple chronic conditions in children, is a growing concern. Its prevalence varies, linked to social factors and early life events, impacting quality of life and healthcare needs.

Area of Science:

  • Pediatric Health
  • Public Health
  • Chronic Disease Epidemiology

Background:

  • Childhood multimorbidity, defined as two or more co-occurring chronic conditions, is an under-researched global health issue.
  • Unlike adult multimorbidity, it impacts critical developmental stages, affecting physical, cognitive, and emotional well-being.
  • Its prevalence, correlates, and long-term implications require further understanding.

Conclusions:

  • Childhood multimorbidity presents substantial health and social challenges, demanding integrated care and standardized definitions for research comparability.
  • Preventive strategies focusing on social determinants and early-life interventions are essential to reduce its long-term burden.
  • Future research should prioritize longitudinal studies to track progression and inform targeted interventions.
Abstract

Keywords:
ChildhoodChronic conditionMultimorbidityPrevalence

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