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Updated: Feb 19, 2026

Drug Repurposing Hypothesis Generation Using the "RE:fine Drugs" System
Published on: December 11, 2016
Optimizing Drug Discovery in Resource-Limited Settings: Multi-Parameter Optimization and Data-Driven Workflows
Aloysius T Nchinda1, Karsten Menzel2
1Holistic Drug Discovery and Development (H3D) Centre, University of Cape Town, Rondebosch 7701, South Africa.
Abstract:
The discovery of novel chemical entities for therapeutic use is a resource-intensive process. Given the constraints of drug discovery resources, it is crucial to allocate assets thoughtfully. This study identifies gaps in research organizations operating under resource limitations and proposes a pragmatic workflow tailored to these settings. This approach uses freely available tools to facilitate the determination of the clearance mechanism for the strategic advancement of chemical entities through data-informed decision-making processes while maximizing the efficiency.
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