Related Experiment Video
Updated: May 11, 2026

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Retroductal Submandibular Gland Instillation and Localized Fractionated Irradiation in a Rat Model of Salivary Hypofunction
Published on: April 24, 2016
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Response to "comment on a submandibular gland-sparing radiotherapy study: a methodological and analytical
Prasoon Garg1, S Shyama Prem1, Madhusudhanan Ponnusamy2
1Department of Radiation Oncology, RCC, JIPMER, Puducherry 605006, India.
Clinical and Translational Radiation Oncology
|February 18, 2026
Summary
This study evaluated scintigraphic assessment of irradiated submandibular glands, finding it a valuable tool for long-term functional evaluation. Sparing these glands during radiation therapy demonstrated oncological safety with no observed recurrences.
Area of Science:
- Nuclear Medicine
- Oncology
- Radiotherapy
Background:
- Submandibular gland (SMG) function is crucial for quality of life after head and neck cancer radiotherapy.
- Assessing SMG function post-irradiation is important for understanding treatment effects and guiding management.
- Scintigraphy offers a functional imaging method to evaluate SMG performance.
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